Abstract:This study determined the residue and dissipation dynamics of pyridaben in cotton leaves and root soil under arid environmental conditions and local planting systems after foliar application of 15% pyridaben emulsion. Four application rates(450-1 125 mL/ha) were set, with one spray application per treatment. Cotton upper leaves and root soil samples were collected at different times within 14 days after application. Samples were analyzed using the QuEChERS method combined with high-performance liquid chromatography (HPLC). According to the established analytical method, within the application rate range of 450-1 125 mL/ha, the initial deposition of pyridaben in cotton leaves after application was 1.11-2.03 mg·kg-1, with a dissipation half-life of 1.35-1.47 days. In soil, the initial deposition was 0.26-0.56 mg·kg-1, with a dissipation half-life of 2.39-2.92 days. Pyridaben was completely dissipated in soil after 14 days. These results indicate that pyridaben is an easily degradable pesticide in this region, which significantly reduces the environmental safety risk after application.