Abstract:Stalk diameter of endemic sorghum varieties in China was studied hy using multivariate regression analysis method of generation mean analysis. The results showed that stalk diameters in F1 were different among different cross combinations, but hetemeis was positive and tended to the parent with high combining ability. Additive effect for stalk diameter was main and 33.2% of total genetic variation. Epistasis effect should be more important than dominant effict, but dominant effect took effect on some cross combinations. Gene effect of 3 cross combinations presented different. Additive effect and dominant effect were positive, and they were the reason that stalk diameter in F1 presented positive heterosls.