Abstract:Dongyu 606, a new multi-resistant and widely adaptable maize variety, was developed by Shenyang Dongyu Seed Industry Co., Ltd. in 2014. Adopting the distant heterosis model of foreign germplasm × domestic germplasm, the variety was bred by integrating traditional conventional breeding techniques with pedigree selection to screen and select parental inbred lines P6270 and K8872, which exhibit high yield potential, strong disease resistance, prominent lodging resistance, and excellent combining ability. This study elaborates on the origin of Dongyu 606 and its parents, as well as the variety's characteristics and yield performance. Additionally, it summarizes high-yield cultivation and seed production techniques, aiming to provide technical support for the promotion of this variety.