Abstract:Fusarium crown rot(FCR) caused by Fusarium pseudograminearum is an important disease worldwide. At present, the prevention and control of FCR is mainly based on chemical control. However, long-term use of chemicals will cause pests to develop resistance, and fungicide compounding is an effective means to slow down resistance. In this study, the effects of different proportions of propiconazole and pyraclostrobin on mycelial growth, spore germination, mycelial micromorphology observation and indoor control effect were carried out in order to obtain the best compound ratio with excellent control effect on FCR. The results showed that in terms of mycelial growth inhibition, the combination of propiconazole and pyraclostrobin at a ratio of 9 : 1 had a synergistic effect on F. pseudograminearum, and 4 : 6 and 7 : 3 were additive. In terms of spore germination inhibition,the combination of propiconazole and pyraclostrobin at a ratio of 4 : 6 had a synergistic effect on F. pseudograminearum, and 2 : 8,3 : 7,5 : 5,6 : 4,7 : 3 and 9 : 1 were additive effects. In addition, the indoor control effect test results showed that when the ratio of propiconazole and pyraclostrobin was 4 : 6, the control effect on FCR was the best, which was 70.45 %. The research results provide data support for the effective prevention and control of FCR, which is of great significance to ensure the safe production of wheat.