Abstract:Salt stress is one of the main environmental factors limiting the growth, development and yield formation of rice. Plant salt tolerance is regulated by multiple factors. As an essential nutrient element and signal molecule for plant growth, nitrogen is involved in various physiological and biochemical metabolic processes. Scientific application of nitrogen fertilizer plays a crucial role in alleviating salt stress-induced damage in rice. However, the main biological processes and mechanisms by which nitrogen regulates rice salt tolerance through scientific nitrogen fertilizer application remain unclear. In particular, there is a lack of molecular-level analysis on the regulation of reproductive growth(e.g., yield components). This review summarizes the research on rice tolerance to salt stress, mainly including the effects of salt stress on rice growth and metabolism, the physiological and molecular response mechanisms, and the regulatory mechanisms of nitrogen nutrition. This review provides theoretical and technical support for optimizing rice production management in saline-alkali areas, as well as target gene resources for molecular breeding of salt-tolerant rice.